Excellence in Biomolecular MS

Establishing a leading research unit at BSRC Fleming to advance biomolecular mass spectrometry and structural biology for biomedical innovation.

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THE PROJECT

Advancing Biomolecular Mass Spectrometry and Structural Biology at BSRC Fleming

MASSTRUCT aims to establish a world class Biomolecular MS Research Unit of Excellence in the Biomedical Sciences Research Centre “Alexander Fleming”. Led by the ERA Chair, Dr Argyris Politis, and team will advance research in biomolecular MS and structural biology, invaluably improving our understanding of fundamental biological processes, and assisting the development of new drug discovery strategies.

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THE PROJECT

Catalyzing Collaborative Innovation and Structural Biology Capacity in Greece

MASSTRUCT will not only open new directions for collaborative research and innovation at BSRC Fleming, but it will also add value to recent EU investments in related disciplines more widely in Greece, and via a network of recently awarded ERA Chairs in Greece focused on complementary structural and chemical approaches. This will build the critical mass for enabling structural biology in Greece, which in turn will leverage downstream research and funding at the interface between chemistry and biology.

Establish a world-class Biomolecular MS Research Unit at BSRC “Alexander Fleming” under the leadership of ERA Chair Dr. Argyris Politis.

Advance research in biomolecular mass spectrometry and structural biology to deepen understanding of biological processes and support drug discovery.

Foster national and international collaboration, linking with ERA Chairs across Greece in complementary scientific fields.

Leverage and amplify recent EU investments to build structural biology capacity and drive innovation at the chemistry–biology interface.

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RESEARCH

Project Research

Scientific mission & impact

Driving innovation in biomolecular MS to advance structural biology and biomedical research.

Science Projects

The project and the Lab will be focusing on two main themes.

Instrumentation & Techniques

State-of-the-art MS technologies and structural analysis methods powering cutting-edge discoveries.

Collaborations

Strategic partnerships with academic and research institutions to enhance scientific outcomes.

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Project Objectives

Project Objective 1

Build an ERA Team of research excellence in BSRC Fleming.

Project Objective 2

Establish the first biomolecular mass spectrometry Research Unit in Greece

Project Objective 3

Develop and maintain an ambitious, world class research agenda

Project Objective 4

Foster collaborative networks with academia and industry

Project Objective 5

Build BSRC Fleming’s excellence and sustainability in Greece and the wider region

Project Objective 6

Build a network of ERA Chairs in biomolecular and protein research in Greece

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Scientific mission & impact

The research group aims to develop the tools and technologies to advance bioscience discovery and innovation. This will in turn improve our fundamental knowledge in better understanding biological processes underpinning human health and disease. A key impact of MASSTRUCT and the associated Group will be to drive the necessary structural and scientific changes to improve people’s health, and to protect, transform and sustain our economy, society, and environment.
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Main Themes

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Science Projects

The project and the Lab will be focusing on two main themes. First, the advancement of technology towards enabling the investigation of challenging protein samples and secondly the exploitation of such technology to unravel disease-related states.

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MASSTRUCT

Career Development

Seminars & Conferences

Seminars and conferences to share research advances, foster collaboration, and engage the scientific community in biomolecular MS and structural biology.

Workshops and summer schools

Hands-on training events to build skills in biomolecular MS and structural biology for students and researchers.

Site visits

Collaborative visits to partner institutions to exchange expertise and strengthen research networks.

Online Communication

Engaging digital platforms and content to share project updates, research outcomes, and connect with the wider community.

Contact us

Let’s connect

2109656310 (ext. 248)

info@masstruct.org

Biomedical Sciences Research Center "Alexander Fleming"

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Contact

Feel free to write us

We’d love to hear from you! Reach out with questions, collaboration ideas, or to learn more about MASSTRUCT.

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MASSTRUCT

News & Events

Talk by Prof. Argyris Politis: ‘Probing the conformational dynamics of membrane proteins by HDX-MS’

MASSTRUCT Team Training at Bruker, Bremen

17–19 June 2025